Tom & Jerry (marketed as Tom & Jerry: The Movie) is a 2021 American live-action/animated slapstick comedy film based on the cartoon characters of the same name created by William Hanna and Joseph Barbera, produced by Warner Animation Group and distributed by Warner Bros. Pictures. It is the second theatrical film based on the characters, following Tom and Jerry: The Movie (1992), and the third to combine live-action and animation, following Anchors Aweigh (1945) and Dangerous When Wet (1953). Set in a world co-populated by humans and cartoon animals, the film follows Tom enlisted to catch Jerry, whose presence threatens New York City's fanciest hotel and its planned high-profile Indian-themed wedding.

The film is directed by Tim Story and written by Kevin Costello. It stars Chloë Grace Moretz, Michael Peña, Colin Jost, Rob Delaney, Pallavi Sharda, Jordan Bolger, Patsy Ferran, and Ken Jeong in live-action roles, with Nicky Jam, Bobby Cannavale, and Lil Rel Howery in voice roles. The titular characters are voiced by William Hanna via archival recordings, with additional vocals from Kaiji Tang and André Sogliuzzo (though the characters are listed as themselves in the credits). Starting with a live-action film in 2009, to an animated film in 2015, and to a hybrid film combining live-action and animation in 2018 (with filming beginning in 2019), the film languished in development hell as the studio spent years finding a writer to pen the most faithful take on the franchise and characters for a feature film. The film also draws inspiration from silent film comedies, such as Charlie Chaplin films, as major reference material for the filmmakers to explore a lot of humor and storytelling associated with silent characters. Other cited influences for the film's story also include Home Alone 2: Lost in New York and Dunston Checks In.Warner Bros. executives wanted the film to “be what Tom and Jerry is”, as “the studio understands how much of its history is rooted in these iconic characters”. Many elements from the original cartoons were featured in the film, such as their sound effects, Tom being a jazz pianist, Tom's Rube Goldberg mouse trap, Jerry's heartbeat, Jerry's theft of food and items, and some of William Hanna's voice tracks for the titular duo. The film pays homage to many classic Tom and Jerry cartoons, including Mouse Trouble (1944), Mouse in Manhattan (1945), and The Cat Concerto (1947).Tom & Jerry was theatrically released by Warner Bros. Pictures in the United States on February 26, 2021, alongside a one-month streaming release on HBO Max. The film received generally negative reviews from critics, who criticized the screenplay for its human cast and lack of ambition, while some praised its blend of animation and live-action, performances, score, entertainment value, nostalgic tone, and faithfulness to the source material. It had grossed $136.5 million worldwide, on a $50‒79 million production budget.