Mr. & Mrs. Smith is a 1941 American screwball comedy film directed by Alfred Hitchcock, written by Norman Krasna, and starring Carole Lombard and Robert Montgomery. It also features Gene Raymond, Jack Carson, Philip Merivale, and Lucile Watson.

Although Mr. & Mrs. Smith was the only pure comedy Hitchcock made in America, he later claimed that he agreed to do it only as a favor to Lombard. However, the files at RKO Radio Pictures show that Hitchcock himself actually pursued the project.