Cybernetics Guardian (聖獣機サイガード, Seijūki Saigādo, lit. Holy Beast Machine Cy-Guard) is an anime original video animation. The original Japanese version was released in 1989 by Anime International Company, and an English Language version in 1996, licensed by Central Park Media. It is about John Stalker who is a research pilot for the fictional Central Guard Company. John was born in the city of Cyber-wood, in an area known as the Cancer Slums. The antagonist of the story, Adler, plans to attack the citizens of the Cancer Slums.

In this Japanese animated science fiction adventure, cities of the future are plagued by violence, and the Central Guard Company is commissioned to find a solution to urban crime. One designer creates a Guard Suit with special psychic powers, while another develops a robotic killing machine that will not only eliminate the bad guys, but also get rid of his romantic rivals in the process. But when John Stalker is given the assignment of testing the Guard Suit, it uncovers a dark and dangerous secret he has kept hidden from the world.