Space Chimps is a 2008 computer-animated comic science fiction film directed by Kirk DeMicco (in his directorial debut), who wrote the screenplay with Rob Moreland. It features the voices of Andy Samberg, Cheryl Hines, Jeff Daniels, Patrick Warburton, Kristin Chenoweth, Kenan Thompson, Zack Shada, Carlos Alazraqui, Omid Abtahi, Patrick Breen, Jane Lynch, Kath Soucie, and Stanley Tucci.

The film follows three chimpanzees who go into space to an alien planet. 20th Century Fox theatrically released the film on July 18, 2008, and received mostly negative reviews by critics. The film grossed $64.8 million on a $37 million budget. It received an Artios Award nomination for Outstanding Achievement in Casting – Animation Feature. A video game based on the film was also released in July 2008.

A direct-to-video sequel, entitled Space Chimps 2: Zartog Strikes Back, was released in October 2010.