Dark Blood is a 2012 American-Dutch thriller film directed by George Sluizer, written by Jim Barton, and starring River Phoenix, Judy Davis, and Jonathan Pryce. The film was not completed due to the death of Phoenix in 1993, shortly before the end of the project (it would also be the final film made by Sluizer) and remained unfinished for 19 years. It was the last film to feature River Phoenix and the only film in which Phoenix portrayed a villain.

It premiered to a private guest audience on September 27, 2012 at the Netherlands Film Festival in Utrecht, Netherlands. The film was shown twice more, publicly, on October 2, 2012 at the festival. It was shown at the 63rd Berlin International Film Festival in February 2013, the Miami International Film Festival in March 2013, the Split Film Festival in September 2013, and the Brussels International Fantastic Film Festival in April 2014. On January 26, 2018, Dark Blood was released on DVD in Germany.

The film follows Boy (Phoenix), a young widower, who retreats to the desert after his wife dies of radiation following nuclear tests near their home. Boy is waiting for the end of the world and carves Kachina dolls, believing they contain magical powers. A couple, Harry (Pryce) and Buffy (Davis) travel to the desert on a second honeymoon in an attempt to save their marriage. Their car breaks down in the middle of nowhere and the couple is rescued by Boy. Boy holds them prisoner because of his desire for Buffy and his ambition to create a better world with her.