Big Jack is a 1949 American Western film starring Wallace Beery, Richard Conte and Marjorie Main. The movie was directed by Richard Thorpe, and the screenplay was written by Gene Fowler and Otto Eis from the novel by Robert Thoeren. The picture is a comedy-drama, set on the American frontier in the early 1800s, about outlaws who befriend a young doctor in legal trouble for acquiring corpses for anatomical research.

This was Wallace Beery's final film, believed to be his 230th. He died on April 15, 1949, at age 64, three days after this movie's release. Also the final film to have a musical score by Herbert Stothart, who had died two months before the film's release.