Vampire Hunter D (Japanese: 吸血鬼ハンターD, Hepburn: Kyūketsuki Hantā Dī) is a 1985 Japanese fantasy horror OVA film produced by Ashi Productions, in association with Epic/Sony Records, CBS/Sony Group Inc. and Movic. The screenplay is based on the first in the long-running series of light novels written by Hideyuki Kikuchi.

Billed by the Japanese producers as a "dark future science-fiction romance", the film, like the novel before it, is set in the year 12,090 AD, in a post-nuclear holocaust world where a young woman hires a mysterious half-vampire, half-human vampire hunter to protect her from a powerful vampire lord. It was one of several anime films featured in the music video for Michael and Janet Jackson's song "Scream".