Pony Express is a 1953 American Western film directed by Jerry Hopper, filmed in Kanab, Utah, and starring Charlton Heston as Buffalo Bill, Forrest Tucker as Wild Bill Hickok, Jan Sterling as a Calamity Jane-type character, and Rhonda Fleming. The story is largely based on the 1925 silent film The Pony Express while the threat of a Californian secession is taken from Frontier Pony Express (1939).

The film is an historical account of the formation of the Pony Express rapid transcontinental mail delivery in the United States in 1860–1861. Although it gives no credit to the real founders of the Pony Express, Buffalo Bill Cody did ride for them, having signed up when he was 15 years old.