Love in the Time of Cholera is a 2007 American romantic drama film directed by Mike Newell. Based on the 1985 novel of the same name by the Colombian Nobel Prize-winning author Gabriel García Márquez, it tells the story of love between Fermina Daza (played by Giovanna Mezzogiorno) and her lover, Florentino Ariza (Javier Bardem) and her husband Juvenal Urbino (Benjamin Bratt) which spans 50 years, from 1880 to 1930.

It is the first filming of a García Márquez novel by a Hollywood studio, rather than by Latin American or Italian directors. It is also the first English-language work of Academy Award-nominated Brazilian actress Fernanda Montenegro, who portrays Tránsito Ariza. Shakira wrote two original songs, "Hay Amores" and "Despedida", for the film.