Sherlock Holmes is an American detective television series syndicated in the autumn of 1954, based on the Sherlock Holmes stories of Arthur Conan Doyle. The 39 half-hour mostly original stories were produced by Sheldon Reynolds and filmed in France by Guild Films, starring Ronald Howard (son of Leslie Howard) as Holmes and H. Marion Crawford as Watson. Archie Duncan appeared in many episodes as Inspector Lestrade (and in a few as other characters). Richard Larke, billed as Kenneth Richards, played Sgt. Wilkins in about fifteen episodes. The series' associate producer, Nicole Milinaire, was one of the first women to attain a senior production role in a television series.

The series was the first American television adaptation of Doyle's stories, and the only such version until 2012's Elementary.