One Little Pill is a documentary film about the use of generic medications (primarily naltrexone, but also nalmefene) for treating and curing alcoholism. The primary focus is on the Sinclair method, which pairs these medications with continued drinking. It was produced by Zard Productions as a film project for the C Three Foundation and released on Vimeo and VHX for on-demand viewing in October 2014. As of August 2015, DVD-R copies are also available.