Appleseed Alpha (also styled as Appleseed α) is a Japanese–American animated military science fiction cyberpunk film. The English version's voice cast includes Luci Christian (Deunan Knute), David Matranga (Briareos) and Wendel Calvert (Two Horns). This film does not follow the previous Appleseed film canon; it is an alternate version of the story's origins. Briareos, for example, is already a cyborg and did not become separated from Deunan to be later reunited in Olympus to join ESWAT. A two-volume prequel manga by Iou Kuroda was published in Morning Two in 2014.

It was announced on February 11, 2014, that Sony Pictures Worldwide and Lucent Pictures Entertainment would be making a new CG-animated film. Appleseed Alpha had an advance digital release on July 15, 2014.