Murder in the Central Committee (Spanish: Asesinato en el Comité Central) is a 1982 Spanish thriller film directed by Vicente Aranda. It stars Patxi Andión and Victoria Abril. The plot follows a private detective, an ex-communist and former CIA agent, who travels from Barcelona to Madrid to discover the identity of the assassin of the leader of the Spanish Communist Party who was stabbed during a blackout while presiding over a meeting of the party's Central Committee. The film is a thriller with ironic political overtones.

The script was written by director Vicente Aranda. It was based on a book of the same name by Manuel Vázquez Montalbán, one of a series of novels that featured the character of a hard-boiled detective called Pepe Carvalho. It was adapted for the screen the year after its publication. Asesinato en el Comité Central was Aranda's first work shot in Madrid instead of his native Barcelona. The film received a cold commercial response.