Scream and Scream Again is a 1970 British horror film starring Vincent Price, Christopher Lee, Alfred Marks, Michael Gothard, and Peter Cushing. It is based on the novel The Disorientated Man (1967) attributed to 'Peter Saxon', a house pseudonym used by various authors in the 1960s and 1970s.

It marks the second teaming, after The Oblong Box, of actors Price and Lee with director Gordon Hessler. Price and Lee only share a brief scene in the film's climax. Cushing, in his brief scene, shares no screen time with either Price or Lee.

Overlooked during its initial release, the film has since become a minor cult classic, with the Overlook Film Guide acknowledging it as "one of the best science-fiction films made in Britain."