Chamber of Horrors is a 1966 American psychological horror film directed by Hy Averback and starring Patrick O'Neal, Cesare Danova, Wilfrid Hyde-White, Wayne Rogers and Laura Devon. The screenplay is by Stephen Kandel, from a story by Kandel and Ray Russell.

The film was released to theatres but was originally shot as a television movie and a pilot film for a proposed series called House of Wax. It was released theatrically because it was considered too intense for television at the time.

The film used the gimmicks of the Fear Flasher (the screen flashing red for several seconds) and the Horror Horn (an audible alert) to alert viewers to grisly moments. The gimmicks were added (including a cameo appearance by Tony Curtis) to increase the running time. There are plot similarities between this and Dark Intruder, which was released the previous year.

The film is narrated by William Conrad.