Mano Po 6: A Mother's Love (simplified Chinese: 母爱; traditional Chinese: 母愛; pinyin: Mǔ'ài; Pe̍h-ōe-jī: Bú-ài) is a 2009 Filipino drama film and the sixth installment of the Mano Po franchise, following Mano Po 5: Gua Ai Di in 2006. Produced by Regal Entertainment, Mano Po 6 marks the first and so far, only appearance of Sharon Cuneta in a Regal Entertainment film outside of her home studios Viva Films and Star Cinema. It co-stars Zsa Zsa Padilla (in her third Mano Po role), Christopher De Leon, Boots Anson-Roa (fourth appearance in the Mano Po series), Kris Aquino (in her third Mano Po role), Dennis Trillo (in another Mano Po appearance, last seen in Mano Po III: My Love), Heart Evangelista, and Ciara Sotto. This is Cuneta's reunion movie with her co-stars Christopher de Leon and Zsa Zsa Padilla from Madrasta. Joel Lamangan, who had last worked with Cuneta in Walang Kapalit directed his fifth Mano Po role.

It is also an entry to the 2009 Metro Manila Film Festival during its theater run from December 25, 2009, to January 2010.