Grand Hotel is a 1932 American pre-Code drama film directed by Edmund Goulding and produced by Metro-Goldwyn-Mayer. The screenplay by William A. Drake is based on the 1930 play by Drake, who had adapted it from the 1929 novel Menschen im Hotel by Vicki Baum. To date, it is the only film to have won the Academy Award for Best Picture without being nominated in any other category.

MGM remade the film as Week-End at the Waldorf in 1945. The German remake Menschen im Hotel was released in 1959, and it served as the basis for the 1989 Tony Award-winning stage musical Grand Hotel. In 1977, MGM announced a musical remake, to take place at Las Vegas' MGM Grand Hotel and directed by Norman Jewison, but the production was cancelled.

Grand Hotel has proven influential in the years since its release. The iconic line "I want to be alone", famously delivered by Greta Garbo, placed number 30 in AFI's 100 Years...100 Movie Quotes. In 2007, the film was selected for preservation in the United States National Film Registry by the Library of Congress for being "culturally, historically, or aesthetically significant".