Dr. Jekyll and Mr. Hyde is a 1920 American silent horror film produced by Famous Players–Lasky and released through Paramount/Artcraft. The film, which stars John Barrymore, is an adaptation of the 1886 novella Strange Case of Dr Jekyll and Mr Hyde by Robert Louis Stevenson. John S. Robertson directed the production, and Clara Beranger wrote the screenplay, based on the 1887 stage play by Thomas Russell Sullivan that in turn was based on the novel.

Set in late Victorian London, the film portrays the tragic consequences of a doctor's experiments in separating the dual personalities he thinks define all humans: one good, the other evil. The film is now in the public domain.