Madame Curie is a 1943 American biographical film made by Metro-Goldwyn-Mayer. The film was directed by Mervyn LeRoy and produced by Sidney Franklin from a screenplay by Paul Osborn, Paul H. Rameau, and Aldous Huxley (uncredited), adapted from the biography by Ève Curie. It stars Greer Garson, Walter Pidgeon, with supporting performances by Robert Walker, Henry Travers, and Albert Bassermann.

The film tells the story of Polish-French physicist Marie Curie in 1890s Paris as she begins to share a laboratory with her future husband Pierre Curie.

This was the fourth of nine onscreen pairings with Pidgeon and Garson.

In several versions, much of the scientific aspects of the film were cut or removed entirely. Turner Classic Movies has shown it unedited at 124 minutes.