Jimmy Neutron's Nicktoon Blast was a simulator ride at Universal Studios Florida that replaced The Funtastic World of Hanna-Barbera based on the 2001 movie Jimmy Neutron: Boy Genius and it is set to take place after the events of the film. The storyline revolves around Ooblar, (brother to King Goobot who is an arch-enemy of Jimmy's) from the Yolkian planet that has stolen Jimmy's newest rocket creation, the Mark IV. Jimmy, along with his best friend Carl and robot dog, Goddard, invite the audience to give chase in other rockets through the worlds and sound stages of the Nicktoons.

On March 14, 2011, Universal announced that the attraction would begin operating on a seasonal schedule starting on April 1, 2011, and would operate for limited amounts of time throughout the spring and summer seasons before it closed completely on August 18, 2011. Jimmy Neutron's Nicktoon Blast was replaced by Despicable Me Minion Mayhem on July 2, 2012, which became part of Minion Land on Illumination Ave.