Manmadhudu is a 2002 Indian Telugu-language romantic comedy film directed by K. Vijaya Bhaskar from a story written by Trivikram Srinivas. The story is based on the 2000 Mel Gibson starrer What Women Want. Produced by Nagarjuna on Annapurna Studios, the film stars Nagarjuna, Sonali Bendre and Anshu, with music composed by Devi Sri Prasad.

Released on 20 December 2002, the film became an All Time Blockbuster. The film received Nandi Award for Best Feature Film for that year. The film was later remade as Aishwarya (2006) in Kannada. A spiritual successor titled Manmadhudu 2 was released in 2019.