Vertigo 2005: Live from Chicago (sometimes titled Vertigo '05: Live from Chicago) is a concert film by Irish rock band U2. It was filmed from 9–10 May 2005 at the United Center in Chicago, Illinois, during the band's Vertigo Tour. The film was released on DVD later that year on 14 November through Island Records in most parts of the world, and on 15 November through Interscope Records in the United States. The DVD was released as a one-disc standard edition and a deluxe edition with a second disc featuring bonus material and a documentary. It was the first of three concert films from the tour.

The video was a worldwide success, topping the music DVD charts in 11 countries. It has been certified diamond in Brazil and France; sextuple-platinum in Australia; triple-platinum in New Zealand, Portugal, and Spain; and double-platinum in Mexico and the United Kingdom. As of January 2007, it was the band's best-selling DVD, according to Nielsen SoundScan, selling over 285,000 copies in the United States.