Charlie Wilson's War is a 2007 American biographical comedy-drama film based on the story of U.S. Congressman Charlie Wilson and CIA operative Gust Avrakotos, whose efforts led to Operation Cyclone, a program to organize and support the Afghan mujahideen during the Soviet–Afghan War (1979–89).

The film was directed by Mike Nichols (his final film) and written by Aaron Sorkin, who adapted George Crile III's 2003 book Charlie Wilson's War: The Extraordinary Story of the Largest Covert Operation in History. It stars Tom Hanks, Julia Roberts, and Philip Seymour Hoffman, with Amy Adams and Ned Beatty in supporting roles. It earned five nominations at the 65th Golden Globe Awards, including Best Motion Picture – Musical or Comedy, and Hoffman earned a Best Supporting Actor nomination at the 80th Academy Awards.