Space-Men (known as Assignment: Outer Space in the United States) is a 1960 Italian science fiction film directed by Antonio Margheriti. The film stars Rik Van Nutter and co-stars Gabriella Farinon, David Montresor, Archie Savage, and Alain Dijon. The film was released in the United States in 1961 by American International Pictures.

Space-Men's storyline recounts a mission in the 22nd century aboard an orbiting space station. The mission involves a risky effort by its crew to redirect a malfunctioning spaceship that threatens to destroy the Earth.