Of Stars and Men is a 1964 animated film from the Hubley family of animators, based on the 1959 book of the same name by astronomer Harlow Shapley, who also narrates. Made in the style of a documentary, it tells of humankind's quest (in the form of a child) to find its place in the universe, through themes such as outer space, physical matter, the meaning of life and the periodic table. There are no character voices; instead, they "talk" through their actions. It has been cited as an example of an "animated documentary".

When it was finished, the film was first screened during a conference at MIT's Visual Department. The film's public premiere was on April 28, 1964, at New York's Beekman Theater, along with a collection of Hubley/U.P.A. shorts (Moonbird and Gerald McBoing-Boing among them) which preceded its showing. The critical reception was uniformly positive.

Its genre was a matter of contention among festival curators. At the Venice Film Festival, Of Stars and Men was placed in the live-action feature category, while at the San Francisco Film Festival, it competed in the documentary category and won an award.

Of Stars and Men received a VHS release from Buena Vista Home Video in July 1990, and had its DVD debut from Image Entertainment nine years later, as part of a compilation of Hubley productions.