Africa Addio (lit. 'Goodbye Africa' or 'Farewell Africa'; also known as Africa: Blood and Guts in the United States and Farewell Africa in the United Kingdom) is a 1966 Italian mondo documentary film co-directed, co-edited and co-written by Gualtiero Jacopetti and Franco E. Prosperi with music by Riz Ortolani. Jacopetti and Prosperi had gained fame (along with co-director Paolo Cavara) as the directors of Mondo Cane in 1962.

Africa Addio documents the end of the colonial era in Africa, and the violence and chaos that followed. The film was a huge success, which ensured the viability of the so-called "Mondo film" genre, a cycle of "shockumentaries"—documentaries featuring sensational topics. The film encountered criticism and praise due to its controversial content, but is nevertheless considered to be a very important film in the history of documentary filmmaking.