Desperate Living is a 1977 American black comedy film directed, produced, and written by John Waters. The film stars Liz Renay, Mink Stole, Susan Lowe, Edith Massey, Mary Vivian Pearce, and Jean Hill.

It is the third installment of what Waters has labeled the "Trash Trilogy", which also includes Pink Flamingos (1972) and Female Trouble (1974), and the only one to not feature Divine. The film generated a cult following around Renay, who appeared in at least two dozen other films.

Following the murder of her husband, a suburban housewife and her maid agree to be exiled to Mortville, a shantytown ruled by a tyrannical queen regnant.