Last Train to Mahakali is a 1999 Indian Hindi-language thriller film written and directed by Anurag Kashyap, produced by Manish Tiwari and Saket Bahl. It was made for the Star Plus television series Star Bestsellers and was first telecast in 1999. The film won the Special Jury Award at the 8th Annual Star Screen Awards. In 2005, it was one of the four short films screened at an event organized by Films Anonymous at Hyderabad.

The film tells the story of a doctor on death row who claims to have discovered a permanent cure for any virus-based disease. It stars Kay Kay Menon and Nivedita Bhattacharya.