Alvin and the Chipmunks: The Squeakquel is a 2009 American live-action/animated jukebox musical comedy film directed by Betty Thomas and written by Jon Vitti and the writing team of Jonathan Aibel and Glenn Berger. It is based on Alvin and the Chipmunks and The Chipettes. It is the second installment in the live-action Alvin and the Chipmunks film series and the sequel to Alvin and the Chipmunks (2007). The film stars Zachary Levi, David Cross and Jason Lee, with voices by Justin Long, Matthew Gray Gubler and Jesse McCartney. Christina Applegate, Anna Faris and Amy Poehler voice the new characters. The film sees the Chipmunks entering high school under the care of Dave Seville's cousin, Toby. Meanwhile, Ian Hawke recruits the Chipettes to restore his career.

Alvin and the Chipmunks: The Squeakquel was released in the United States on December 23, 2009, by 20th Century Fox. The film received generally negative reviews from critics, who criticized the over-reliance of juvenile humor. However, it grossed $443.1 million worldwide against a $70 million budget. Two sequels were later released: Alvin and the Chipmunks: Chipwrecked in 2011 and Alvin and the Chipmunks: The Road Chip in 2015.