Skinwalkers is a 2006 action horror film. It was released in the United States by Lions Gate Entertainment and After Dark Films, and focuses on werewolves. Directed by James Isaac, it stars Jason Behr, Elias Koteas, Rhona Mitra, and Tom Jackson. The film was originally announced for theatrical release on December 1, 2006, but was delayed until August 10, 2007.

Skinwalkers marks Lions Gate Entertainment's first collaboration with Constantin Film, which produced such other science fiction/horror films as Resident Evil and Wrong Turn. The visual effects are by effects house Mr. X, and the creature effects by Stan Winston Studio.

The film was shot at Century Manor in Hamilton, Ontario, Canada, and in Creemore Ontario. To achieve a PG-13 rating, the production team cut several scenes containing graphic violence — the home media release is the uncut version of the film.