Nutty Professor II: The Klumps is a 2000 American science fiction comedy film directed by Peter Segal and starring Eddie Murphy and Janet Jackson. It is the second and final installment in the Nutty Professor remake film series and the sequel to the 1996 film The Nutty Professor.

In contrast to the previous film, subplots centered on the parents of protagonist Sherman Klump occupy a substantial part of the film. Like the first film, the sequel's theme song is "Macho Man" by Village People, which this time is played during the end credits.

The film was parodied by comedian Jack Black in Tropic Thunder (2008), in which Black's character Jeff Portnoy plays various members of a comically obese family. Tropic Thunder was released by Paramount Pictures, which had released the original version of the film, starring Jerry Lewis, in 1963. Tropic Thunder was directed by and starred Ben Stiller, who later starred opposite Eddie Murphy in Tower Heist (2011).