Fabienne, a beautiful 45-year-old woman, a family mother and business manager, discovers with upheaval that she is suffering from an early and galloping Alzheimer's disease. Leaving her home, one morning, forgetting where she comes from and where she goes, Fabienne meets a man – a marginal, with whom she takes the road for a 48-hour road movie and a night. In parallel, her family, in deep concern, starts looking for a vulnerable adult who has disappeared.

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