Anacondas: The Hunt for the Blood Orchid is a 2004 American action adventure horror film directed by Dwight H. Little. It is a stand-alone sequel to the film Anaconda (1997) and the second installment of the Anaconda film series. It stars Johnny Messner, KaDee Strickland, Matthew Marsden, Eugene Byrd, Salli Richardson-Whitfield, Nicholas Gonzalez, Karl Yune and Morris Chestnut. The film follows a team of researchers set for an expedition into the Southeast Asian tropical island of Borneo, to search for a sacred flower which they believe will bring humans to a longer and healthier life. They soon become stalked and hunted by the deadly giant anacondas inhabiting the island.

It was released on August 27, 2004, and the last film in the series to be released theatrically, until 2025. Like its predecessor, the film received negative reviews but was a financial success. The film was followed by a sequel, Anaconda 3: Offspring in 2008.