The Facts of Life Reunion is a 2001 American made-for-television comedy-drama film based on the 1979–1988 NBC sitcom The Facts of Life which reunited original cast members Charlotte Rae, Lisa Whelchel, Mindy Cohn and Kim Fields. Nancy McKeon was unable to participate due to scheduling conflicts with her then-starring role in the television series The Division.

The film originally aired on ABC as a presentation of The Wonderful World of Disney on November 18, 2001. It is the third television film based on the series and is preceded by The Facts of Life Goes to Paris (1982) and The Facts of Life Down Under (1987).