The Big Store is a 1941 American comedy film directed by Charles Reisner and starring the Marx Brothers (Groucho, Harpo and Chico) that takes place in a large department store. Groucho appears as private detective Wolf J. Flywheel (a character name originating from the Marx-Perrin radio show Flywheel, Shyster, and Flywheel in the early 1930s).

The Big Store was the last of the five films that the Marx Bros. made under contract to Metro-Goldwyn-Mayer. The Marxes had decided to retire as a team and The Big Store was advertised as their farewell film. However, they would return to the screen in A Night in Casablanca (1946) and Love Happy (1949).

The film also features singer Tony Martin and Virginia Grey as the love interests and longtime Marx Brothers foil Margaret Dumont in her seventh and final film with the Marxes. The villain is portrayed by Douglass Dumbrille, who had played a similar role in A Day at the Races (1937).