Demetrius and the Gladiators is a 1954 American biblical drama film and a sequel to The Robe. The picture was made by 20th Century-Fox, directed by Delmer Daves and produced by Frank Ross. The screenplay was written by Philip Dunne based on characters created by Lloyd C. Douglas in The Robe.

The movie presents Victor Mature as Demetrius, a Christian slave made to fight in the Roman arena as a gladiator, and Susan Hayward as Messalina, a reprobate who is the wife of Claudius, the uncle of the depraved emperor Caligula. The cast also features Ernest Borgnine, William Marshall, Michael Rennie, Jay Robinson as Caligula, Debra Paget, Anne Bancroft in one of her earlier roles, and Julie Newmar as a briefly seen dancing entertainer. The film is in Technicolor and CinemaScope.