The Ghost of Frankenstein is a 1942 American horror film directed by Erle C. Kenton and starring Cedric Hardwicke, Lon Chaney Jr. and Bela Lugosi. It is the fourth film in the Frankenstein series by Universal Pictures, and the follow-up to Son of Frankenstein (1939). The film's plot follows the previous film's plot: Frankenstein's Monster (Lon Chaney Jr.) and his companion Ygor (Bela Lugosi) are chased out of town. They go to another small town to encourage the younger son of Henry Frankenstein (Cedric Hardwicke) to continue his father's experiments, so that Ygor can have revenge against his enemies and his brain transplanted into the Monster's skull.

The film was the first in the series with Chaney portraying the monster and was cast one day after the film was announced by Universal. It began production in December 1941 and finished in January 1942. On its release it received praise as being as strong as the previous films from The Hollywood Reporter and The Motion Picture Herald while it received negative reviews from New York Daily News and The New York Times.