Mr. Bones is a 2001 South African comedy film directed by Gray Hofmeyr. Leon Schuster starred in the title role. He also created the story and co-wrote the screenplay. The film sets African "tradition" in opposition to forces of ambition and greed in contemporary South Africa, and plays on reversals of racial stereotypes for its humour.

The film grossed R33 million, making it the highest grossing South African film of all time, until it was beaten by its sequel, Mr Bones 2: Back from the Past (grossing R35 million), itself surpassed by Titanic in South Africa's box-office history.