Epidemic is a 1987 Danish experimental medical dark comedy-horror film co-written and directed by Lars von Trier; it is the second installment of Trier's Europa trilogy, following The Element of Crime (1984) and succeeded by Europa (1991).

Co-written by Trier and Niels Vørsel, the film focuses on the screenwriting process. Vørsel and Trier play themselves, coming up with a last-minute script for a producer. The story is inter-cut with scenes from the film they write, in which Trier plays a renegade doctor trying to cure a modern-day epidemic. The film marks the first in a series of collaborations between Trier and Udo Kier.