Lassie Come Home is a 1943 Metro-Goldwyn-Mayer Technicolor feature film starring Roddy McDowall and canine actor Pal, in a story about the profound bond between Yorkshire boy Joe Carraclough and his rough collie, Lassie. The film was directed by Fred M. Wilcox from a screenplay by Hugo Butler based upon the 1940 novel Lassie Come-Home by Eric Knight. The film was the first in a series of seven MGM films starring "Lassie."

The original film saw a sequel, Son of Lassie in 1945 with five other films following at intervals through the 1940s. A British remake of the 1943 movie was released in 2005 as Lassie to moderate success. The film has been released to VHS and DVD.

In 1993, Lassie Come Home was included in the annual selection of 25 motion pictures added to the National Film Registry of the Library of Congress being deemed "culturally, historically, or aesthetically significant" and recommended for preservation.