Extreme Prejudice is a 1987 American neo-Western action thriller film directed by Walter Hill, from a screenplay by Harry Kleiner and Deric Washburn, from a story by John Milius and Fred Rexer. It stars Nick Nolte and Powers Boothe, with a supporting cast including Michael Ironside, María Conchita Alonso, Rip Torn, William Forsythe, and Clancy Brown.

Set in South Texas near the U.S.-Mexico border, the film's plot centers on the conflict between two former friends-turned-rivals, one a Texas Ranger (Nolte) and one a drug trafficker (Boothe), who both become embroiled in a political conspiracy involving a black ops military unit. The film was released by Tri-Star Pictures on April 24, 1987. It received a positive critical response, but was not a financial success.

Extreme Prejudice is an homage, of sorts, to The Wild Bunch, a western directed by Sam Peckinpah, with whom Hill worked on The Getaway. Both films end with a massive gunfight in a Mexican border town. The title originates from "terminate with extreme prejudice", a phrase popularized by Apocalypse Now, also written by Milius.