Smith & Wesson is a 1988 Filipino action comedy film co-written and directed by Tony Y. Reyes. It stars Vic Sotto and Joey de Leon as the titular duo, alongside Beverly Vergel, Panchito, Paquito Diaz, Mon Alvir, Angela Luz, Jimmy Fabregas, Rene Requiestas, and Vangie Labalan. Sotto and de Leon are also the film's co-writers and producers. The film parodies both Miami Vice and Bloodsport, with the title in reference to the American firearm manufacturer of the same name.

Smith & Wesson was released by Viva Films on November 16, 1988. The film was praised by critic Lav Diaz for its playful mood and Requiestas' naturally comedic performance, though he criticized the demeaning treatment of women and little people.

The film is streaming online on YouTube.