Invicta FC 5: Penne vs. Waterson was a mixed martial arts event held on April 5, 2013. Shannon Knapp announced during Invicta FC 4 that the event will be headlined by a co-main event of Jessica Penne defending her Invicta FC Atomweight Championship against "The Karate Hottie" Michelle Waterson along with a flyweight championship bout between Vanessa Porto and Barb Honchak and that Sarah Kaufman would make her Invicta debut on the show. The show was originally targeted for April 13, however Knapp announced they would change it to April 5 after the UFC announced a show on that date.

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