Clifford the Big Red Dog is a 2021 live-action animated fantasy comedy film directed by Walt Becker from a screenplay by Blaise Hemingway and the writing team of Jay Scherick and David Ronn, and a story by Justin Malen and Ellen Rapoport, based on the children's book series by Norman Bridwell. The film stars Jack Whitehall, Darby Camp, Tony Hale, Sienna Guillory, David Alan Grier, Russell Wong, Izaac Wang, Kenan Thompson and John Cleese.

The film was screened unannounced on August 26, 2021, during the 2021 CinemaCon event in Los Angeles. It was initially scheduled to premiere at the 2021 Toronto International Film Festival in September 2021, to be followed by a theatrical release in the United States on September 17 after being delayed due to the COVID-19 pandemic by Paramount Pictures, but was ultimately pulled from the festival and had its release date removed from Paramount's schedule due to the spread of the SARS-CoV-2 Delta variant. Ultimately, the film was simultaneously released theatrically and digitally on Paramount+ on November 10, 2021, in the United States. It received mixed to positive reviews from critics and grossed $107 million worldwide on a $64 million budget. A sequel is in development.