Jay and Seth Versus the Apocalypse is a 2007 American apocalyptic science fiction action comedy short film written and directed by Jason Stone and co-written by Seth Rogen and Evan Goldberg. The film, a 10-minute short, stars actors Seth Rogen and Jay Baruchel. Initially an 85-second trailer was uploaded to YouTube containing some lines of dialogue that were not included in the full 10-minute short later uploaded to YouTube. It was later adapted into a theatrical feature-length film titled This Is the End (2013) and fully released on its full-length counterpart's Blu-ray release.

Jay and Seth Versus the Apocalypse follows fictionalized versions of the two actors who have shut themselves in their apartment and argue over their predicament during some unspecified end-of-the-world event.