The Cannonball Run is a 1981 action-comedy film directed by Hal Needham, produced by Hong Kong firm Golden Harvest, and distributed by 20th Century-Fox. Filmed in Panavision, it features an all-star ensemble cast, including Burt Reynolds, Dom DeLuise, Roger Moore, Farrah Fawcett, Jackie Chan, Sammy Davis Junior and Dean Martin. The film is based on the 1979 running of the Cannonball Baker Sea-to-Shining-Sea Memorial Trophy Dash, an actual cross-country outlaw road race beginning in Connecticut and ending in California.

It was the sixth-highest-grossing domestic film of 1981 and became the first installment of the Cannonball Run trilogy. It was followed by Cannonball Run II (1983) (which was far less successful at the box office and with critics) and Speed Zone (1989). This film and its sequel were the final film appearances of actor Dean Martin. It also featured Jackie Chan in his second Hollywood role.

Cannonball (1976) and The Gumball Rally (1976) were two other motion pictures based on the actual Cannonball Run outlaw road race.