WWE Fatal 4-Way was a professional wrestling pay-per-view (PPV) event produced by World Wrestling Entertainment (WWE). It was held for wrestlers from the promotion's Raw and SmackDown brand divisions. The event took place on June 20, 2010, at the Nassau Coliseum in Uniondale, New York. The show was based around a few matches on the card being contested as fatal four-way matches. Fatal 4-Way replaced The Bash as the June 2010 PPV.

The event received 143,000 pay-per-view buys, down on The Bash's figure of 178,000 buys. This was the final WWE pay-per-view event to be held in Nassau Coliseum before its 2015 renovation. This was the only Fatal 4-Way PPV produced by WWE for their main roster, as it was replaced by Capitol Punishment in 2011; however, the promotion revived the name for their developmental territory NXT in 2014 as the brand's second TakeOver event titled NXT TakeOver: Fatal 4-Way.