Killer Ape (1953) is the twelfth Jungle Jim film produced by Columbia Pictures. It features Johnny Weissmuller in his twelfth performance as the protagonist adventurer Jungle Jim. Carol Thurston also stars. The film was directed by Spencer G. Bennet and written by Arthur Hoerl and Carroll Young.

The film centres on Jungle Jim battling a man-like ape in the jungle and trying to clear his name after he is framed of murder. The film was theatrically released in the United States in December 1953.