House of Cards is a 1968 American neo-noir crime film directed by John Guillermin and starring George Peppard, Inger Stevens, and Orson Welles. Filmed in France and Italy, it marked the third time that Peppard and Guillermin worked together (they had previously collaborated on the 1966 film The Blue Max, then P.J.).

The film was first released in the United Kingdom in November 1968, but was not released in the United States until the following September.