Shark Attack 3: Megalodon is the second sequel to Shark Attack, released in 2002 direct-to-video. The film is notable for featuring John Barrowman, who later found fame in popular shows such as Doctor Who and Torchwood. Barrowman has said in an interview on Friday Night with Jonathan Ross that he only did the film for the money (on QI, he claimed it paid for his first house), and was rather embarrassed when a clip from the film was shown. Actress Jenny McShane from the first Shark Attack film has a starring role, albeit as a completely different character.

When two researchers discover a colossal shark's tooth off the Mexican coast their worst fears surface - the most menacing beast to ever rule the waters, Megalodon, is still alive and mercilessly feeding on anything that crosses its path. The film is also notable because certain clips from it have become popular internet memes due to the unconvincing special effects, size-changing shark, and bizarre dialogue.